Transcobalamin II Receptor Polymorphisms Are Associated with Increased Risk for Neural Tube Defects

OBJECTIVE: Women who have low cobalamin (vitamin B12) levels are at increased risk for having children with neural tube defects (NTDs). The transcobalamin II receptor (TCblR) mediates uptake of cobalamin into cells. We evaluated inherited variants in the TCblR gene as NTD risk factors. METHODS: Case...

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Hoofdauteurs: Pangilinan, Faith, Mitchell, Adam, VanderMeer, Julie, Molloy, Anne M., Troendle, James, Conley, Mary, Kirke, Peadar N., Sutton, Marie, Sequeira, Jeffrey M., Quadros, Edward V., Scott, John M., Mills, James L., Brody, Lawrence C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112773/
https://ncbi.nlm.nih.gov/pubmed/20577008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2009.073775
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