Estrogenic activity in vivo and in vitro of some diethylstilbestrol metabolites and analogs

The diethylstilbestrol (DES) metabolite (β-dienestrol), which had been identified in mouse, rat, monkey, and human urine, and two proposed metabolic intermediates (diethylstilbestrol α,α′-epoxide and α,α′-dihydroxy DES) were synthesized and their estrogenic activities determined. In addition, three...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Korach, Kenneth S., Metzler, Manfred, McLachlan, John A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1978
Schlagworte:	Biological Sciences: Medical Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.468
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