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Nanoparticle Delivery of Transition-Metal Chelators to the Brain: Oxidative Stress will Never See it Coming!

The pathological lesions typical of Alzheimer disease (AD) are sites of significant and abnormal metal accumulation. Metal chelation therapy, therefore, provides a very attractive therapeutic measure for the neuronal deterioration of AD, though its institution suffers fundamental deficiencies. Namel...

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Detalhes bibliográficos
Main Authors: Bonda, David J., Liu, Gang, Men, Ping, Perry, George, Smith, Mark A., Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112585/
https://ncbi.nlm.nih.gov/pubmed/22229318
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