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Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques

Macrophages play an important role in HIV/SIV pathogenesis by serving as a reservoir for viral persistence in brain and other tissues. Infected macrophages have been detected in brain early after infection, but macrophage-tropic viruses are rarely isolated until late-stage infection. Little is known...

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Hlavní autoři: Yen, Po-Jen, Mefford, Megan E, Hoxie, James A., Williams, Kenneth C., Desrosiers, Ronald C., Gabuzda, Dana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112485/
https://ncbi.nlm.nih.gov/pubmed/24928039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.03.024
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