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Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation

BACKGROUND: The majority of human embryos created using in vitro fertilisation (IVF) techniques are aneuploid. Comprehensive chromosome screening methods, applicable to single cells biopsied from preimplantation embryos, allow reliable identification and transfer of euploid embryos. Recently, random...

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Main Authors: Wells, Dagan, Kaur, Kulvinder, Grifo, Jamie, Glassner, Michael, Taylor, Jenny C, Fragouli, Elpida, Munne, Santiago
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112454/
https://ncbi.nlm.nih.gov/pubmed/25031024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2014-102497
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