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Invariant Local Conformation in p22(phox) p.Y72H Polymorphisms Suggested by Mass Spectral Analysis of Crosslinked Human Neutrophil Flavocytochrome b

The NADPH oxidase of phagocytic leukocytes generates superoxide that plays a critical role in innate immunity and inflammatory responses. The integral membrane protein flavocytochrome b (Cyt b, a.k.a. cytochrome b(558/559)) is the catalytic core of the complex and serves as a prototype for homologs...

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Detalhes bibliográficos
Main Authors: Taylor, Ross M., Dratz, Edward A., Jesaitis, Algirdas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112180/
https://ncbi.nlm.nih.gov/pubmed/21640156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2011.05.004
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