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Specific binding of messenger RNA and methionyl-tRNAfMet by the same initiation factor for eukaryotic protein synthesis.

Affinity chromatography on columns containing globin mRNA, R17 phage mRNA, or double-stranded RNA linked to cellose is used to demonstrate unequivocally that the eukaryotic initiation factor (eIF-2) that forms a ternary complex with Met-tRNAf and GTP also binds tightly to these RNA species. Affinity...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kaempfer, R, Hollender, R, Abrams, W R, Israeli, R
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.209
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