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Identification of In Vitro Metabolites of Amoxicillin in Human Liver Microsomes by LC–ESI/MS
Amoxicillin (AMOX) metabolism in human liver microsomes was studied in vitro using liquid chromatography–mass spectrometry (LC/MS). Amoxicillin was incubated with human liver microsomes along with NADPH, and the reaction mixture was analyzed by LC/MS to obtain the specific metabolic profile of the s...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111861/ https://ncbi.nlm.nih.gov/pubmed/25089048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10337-014-2648-2 |
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