Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer disease spectrum

BACKGROUND: Impairment in instrumental activities of daily living (IADL) heralds the transition from mild cognitive impairment (MCI) to dementia and is a major source of burden for both the patient and caregiver. OBJECTIVE: To investigate the relationship between IADL and regional cortical thinning...

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Hauptverfasser: Marshall, Gad A., Lorius, Natacha, Locascio, Joseph J., Hyman, Bradley T., Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111766/
https://ncbi.nlm.nih.gov/pubmed/24685624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-132768
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