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Fos-dependent induction of Chk1 protects osteoblasts from replication stress
Stable Fos expression in the osteoblast lineage results in the development of osteosarcomas (OS) in mice, yet the underlying mechanisms are poorly understood. Using a genetic system in which Fos expression can be induced in osteoblasts in a doxycycline-dependent manner and through subsequent RNA seq...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111761/ https://ncbi.nlm.nih.gov/pubmed/24762558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28923 |
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