Mucosal poly IC improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity

Live-attenuated influenza vaccines (LAIV) have the potential to generate CD8 T cell immunity that may limit the virulence of an antigenically shifted influenza strain in a population lacking protective antibodies. However, current LAIVs exert limited T cell immunity restricted to the vaccine strains...

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Detalhes bibliográficos
Main Authors: Pérez-Girón, José V., Belicha-Villanueva, Alan, Hassan, Ebrahim, Gómez-Medina, Sergio, Cruz, Jazmina L.G., Lüdtke, Anja, Ruibal, Paula, Albrecht, Randy A., García-Sastre, Adolfo, Muñoz-Fontela, César
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111144/
https://ncbi.nlm.nih.gov/pubmed/24958904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400222
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