Association of cancer metabolism-related proteins with oral carcinogenesis – indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?

BACKGROUND: Tumor metabolism is a crucial factor for the carcinogenesis of oral squamous cell carcinoma (OSCC). METHODS: Expression of IGF-R1, glycolysis-related proteins (GLUT-1, HK 2, PFK-1, LDHA, TKTL1), mitochondrial enzymes (SDHA, SDHB, ATP synthase) were analyzed in normal oral mucosa (n = 5),...

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Main Authors: Grimm, Martin, Cetindis, Marcel, Lehmann, Max, Biegner, Thorsten, Munz, Adelheid, Teriete, Peter, Kraut, Wiebke, Reinert, Siegmar
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110933/
https://ncbi.nlm.nih.gov/pubmed/25048361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-208
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