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Visual Detection of Single-Base Mismatches in DNA Using Hairpin Oligonucleotide with Double-Target DNA Binding Sequences and Gold Nanoparticles

We describe a hairpin oligonucleotide (HO) with double-target DNA binding sequences in the loop and 11-base in the stem for visual detection of single-base mismatches (SBM) in DNA with highly specificity. The thiol-modified HO was immobilized on gold nanoparticle (Au-NP) surface through a self-assem...

詳細記述

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書誌詳細
主要な著者: He, Yuqing, Zhang, Xibao, Zhang, Sanquan, Kris, Mak Ka Long, Man, Fong Chi, Liu, Guodong
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110906/
https://ncbi.nlm.nih.gov/pubmed/22386491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2011.12.055
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