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Towards a better understanding of QT interval variability

The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) Guideline E14 recommends ‘Thorough QT Study’ as a standard assessment of drug-induced QT interval prolongation. At the same time, the value of drug-induced QTc prolongation...

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Detalhes bibliográficos
Main Authors: Tereshchenko, Larisa G., Berger, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110835/
https://ncbi.nlm.nih.gov/pubmed/25083216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2042098611421209
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