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Does design matter? Systematic evaluation of the impact of analytical choices on effect estimates in observational studies

BACKGROUND: Clinical studies that use observational databases, such as administrative claims and electronic health records, to evaluate the effects of medical products have become commonplace. These studies begin by selecting a particular study design, such as a case control, cohort, or self-control...

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Bibliographic Details
Main Authors: Madigan, David, Ryan, Patrick B., Schuemie, Martijn
Format: Artigo
Language:Inglês
Published: SAGE Publications 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110833/
https://ncbi.nlm.nih.gov/pubmed/25083251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2042098613477445
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