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Structure prediction of polyglutamine disease proteins: comparison of methods

BACKGROUND: The expansion of polyglutamine (poly-Q) repeats in several unrelated proteins is associated with at least ten neurodegenerative diseases. The length of the poly-Q regions plays an important role in the progression of the diseases. The number of glutamines (Q) is inversely related to the...

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Main Authors: Wen, Jingran, Scoles, Daniel R, Facelli, Julio C
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110737/
https://ncbi.nlm.nih.gov/pubmed/25080018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S7-S11
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