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Structure prediction of polyglutamine disease proteins: comparison of methods

BACKGROUND: The expansion of polyglutamine (poly-Q) repeats in several unrelated proteins is associated with at least ten neurodegenerative diseases. The length of the poly-Q regions plays an important role in the progression of the diseases. The number of glutamines (Q) is inversely related to the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wen, Jingran, Scoles, Daniel R, Facelli, Julio C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110737/
https://ncbi.nlm.nih.gov/pubmed/25080018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S7-S11
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