A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival

BACKGROUND: BRCA1 mutation carriers have an 85% risk of developing breast cancer but the risk of developing non-hereditary breast cancer is difficult to assess. Our objective is to test whether a DNA methylation (DNAme) signature derived from BRCA1 mutation carriers is able to predict non-hereditary...

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Библиографические подробности
Главные авторы: Anjum, Shahzia, Fourkala, Evangelia-Ourania, Zikan, Michal, Wong, Andrew, Gentry-Maharaj, Aleksandra, Jones, Allison, Hardy, Rebecca, Cibula, David, Kuh, Diana, Jacobs, Ian J, Teschendorff, Andrew E, Menon, Usha, Widschwendter, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110671/
https://ncbi.nlm.nih.gov/pubmed/25067956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm567
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