Preparation and nanoencapsulation of l-asparaginase II in chitosan-tripolyphosphate nanoparticles and in vitro release study

This paper describes the production, purification, and immobilization of l-asparaginase II (ASNase II) in chitosan nanoparticles (CSNPs). ASNase II is an effective antineoplastic agent, used in the acute lymphoblastic leukemia chemotherapy. Cloned ASNase II gene (ansB) in pAED4 plasmid was transform...

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Main Authors: Bahreini, Elham, Aghaiypour, Khosrow, Abbasalipourkabir, Roghayeh, Mokarram, Ali Rezaei, Goodarzi, Mohammad Taghi, Saidijam, Massoud
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2014
Assuntos:
Nano Express
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110547/
https://ncbi.nlm.nih.gov/pubmed/25114635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1556-276X-9-340
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