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Implications of the E-selectin S128R mutation for drug discovery
The C-type lectin E-selectin mediates the rolling of circulating leukocytes on vascular endothelial cells during the inflammatory process. In numerous studies, the S128R mutation of the E-selectin was associated with cardiovascular and autoimmune diseases. There is evidence that the S128R E-selectin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110475/ https://ncbi.nlm.nih.gov/pubmed/24688092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu026 |
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