Implications of the E-selectin S128R mutation for drug discovery

The C-type lectin E-selectin mediates the rolling of circulating leukocytes on vascular endothelial cells during the inflammatory process. In numerous studies, the S128R mutation of the E-selectin was associated with cardiovascular and autoimmune diseases. There is evidence that the S128R E-selectin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Preston, Roland C, Rabbani, Said, Binder, Florian P C, Moes, Suzette, Magnani, John L, Ernst, Beat
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110475/
https://ncbi.nlm.nih.gov/pubmed/24688092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu026
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