A randomized trial of a single-dose rasburicase versus five-daily doses in patients at risk for tumor lysis syndrome

BACKGROUND: Tumor lysis syndrome (TLS) is a life-threatening disorder characterized by hyperuricemia and metabolic derangements. The efficacy of rasburicase, administered daily for 5 days, has been well established. However, the optimal duration of therapy is unknown in adults. PATIENTS AND METHODS:...

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Detalhes bibliográficos
Main Authors: Vadhan-Raj, S., Fayad, L. E., Fanale, M. A., Pro, B., Rodriguez, A., Hagemeister, F. B., Bueso-Ramos, C. E., Zhou, X., McLaughlin, P. W., Fowler, N., Shah, J., Orlowski, R. Z., Samaniego, F., Wang, M., Cortes, J. E., Younes, A., Kwak, L. W., Sarlis, N. J., Romaguera, J. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110463/
https://ncbi.nlm.nih.gov/pubmed/22015451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdr490
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