Tryparedoxin peroxidase of Leishmania braziliensis: homology modeling and inhibitory effects of flavonoids for anti-leishmanial activity

Inhibition of the Tryparedoxin peroxidase interaction has been becomes a new therapeutic strategy in leishmaniasis. Docking analysis was carried out to study the effects of quercetin and taxifolin on Tryparedoxin Peroxidase (TryP). Tryparedoxin peroxidase of Trypanosomatidae functions as antioxidant...

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Hlavní autoři: Gundampati, Ravi Kumar, Sahu, Shraddha, Shukla, Ankita, Pandey, Rajesh Kumar, Patel, Monika, Banik, Rathindra Mohan, Jagannadham, Medicherla Venkata
Médium: Artigo
Jazyk:Inglês
Vydáno: Biomedical Informatics 2014
Témata:
Hypothesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110426/
https://ncbi.nlm.nih.gov/pubmed/25097378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010353
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