Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation

Retromer is a protein assembly that plays a central role in orchestrating export of transmembrane-spanning cargo proteins from endosomes into retrieval pathways destined for the Golgi apparatus and the plasma membrane [1]. Recently, a specific mutation in the retromer component VPS35, VPS35(D620N),...

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Bibliografski detalji
Glavni autori: McGough, Ian J., Steinberg, Florian, Jia, Da, Barbuti, Peter A., McMillan, Kirsty J., Heesom, Kate J., Whone, Alan L., Caldwell, Maeve A., Billadeau, Daniel D., Rosen, Michael K., Cullen, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2014
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110399/
https://ncbi.nlm.nih.gov/pubmed/24980502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.06.024
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