Lack of influence of the COX inhibitors metamizol and diclofenac on platelet GPIIb/IIIa and P-selectin expression in vitro

BACKGROUND: The effect of non-steroidal anti-inflammatory drugs (NSAIDs) for reduced platelet aggregation and thromboxane A(2 )synthesis has been well documented. However, the influence on platelet function is not fully explained. Aim of this study was to examine the influence of the COX-1 inhibitin...

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Bibliografiske detaljer
Main Authors: Scheinichen, Dirk, Elsner, Holger-Andreas, Osorio, Rodin, Jüttner, Björn, Gröschel, Werner, Jaeger, Karsten, Piepenbrock, Siegfried
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC411036/
https://ncbi.nlm.nih.gov/pubmed/15107131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2253-4-4
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