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Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
Toxin YafQ functions as a ribonuclease in the dinJ-yafQ toxin-antitoxin system of Escherichia coli. Antitoxin DinJ neutralizes YafQ-mediated toxicity by forming a stable protein complex. Here, crystal structures of the (DinJ)(2)-(YafQ)(2) complex and the isolated YafQ toxin have been determined. The...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110321/ https://ncbi.nlm.nih.gov/pubmed/24923448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559773 |
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