The Influence of Prior Abiraterone Treatment on the Clinical Activity of Docetaxel in Men with Metastatic Castration-resistant Prostate Cancer

BACKGROUND: Taxanes may partly mediate their effect in castration-resistant prostate cancer (CRPC) through disruption of androgen-receptor trafficking along microtubules. This raises the possibility of cross-resistance between androgen-directed agents and docetaxel. OBJECTIVE: To evaluate docetaxel...

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Detalhes bibliográficos
Main Authors: Schweizer, Michael T., Zhou, Xian C., Wang, Hao, Bassi, Sunakshi, Carducci, Michael A., Eisenberger, Mario A., Antonarakis, Emmanuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110192/
https://ncbi.nlm.nih.gov/pubmed/24491307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2014.01.018
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