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LITAF Mutations Associated with Charcot-Marie-Tooth Disease 1C Show Mislocalization from the Late Endosome/Lysosome to the Mitochondria

Charcot-Marie-Tooth (CMT) disease is one of the most common heritable neuromuscular disorders, affecting 1 in every 2500 people. Mutations in LITAF have been shown to be causative for CMT type 1C disease. In this paper we explore the subcellular localization of wild type LITAF and mutant forms of LI...

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Hlavní autoři: Ferreira Lacerda, Andressa, Hartjes, Emily, Brunetti, Craig R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110028/
https://ncbi.nlm.nih.gov/pubmed/25058650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103454
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