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UVB Induces a Genome-Wide Acting Negative Regulatory Mechanism That Operates at the Level of Transcription Initiation in Human Cells

Faithful transcription of DNA is constantly threatened by different endogenous and environmental genotoxic effects. Transcription coupled repair (TCR) has been described to stop transcription and quickly remove DNA lesions from the transcribed strand of active genes, permitting rapid resumption of b...

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Detalhes bibliográficos
Main Authors: Gyenis, Ákos, Umlauf, David, Újfaludi, Zsuzsanna, Boros, Imre, Ye, Tao, Tora, Làszlò
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109906/
https://ncbi.nlm.nih.gov/pubmed/25058334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004483
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