Transfer and functional consequences of dietary microRNAs in vertebrates: Concepts in search of corroboration: Negative results challenge the hypothesis that dietary xenomiRs cross the gut and regulate genes in ingesting vertebrates, but important questions persist

If validated, diet-derived foreign microRNA absorption and function in consuming vertebrates would drastically alter our understanding of nutrition and ecology. RNA interference (RNAi) mechanisms of Caenorhabditis elegans are enhanced by uptake of environmental RNA and amplification and systemic dis...

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Autores principales: Witwer, Kenneth W, Hirschi, Kendal D
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2014
Materias:
Prospects & Overviews
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109825/
https://ncbi.nlm.nih.gov/pubmed/24436255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300150
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