Requirement of dual stimulation by homologous recombinant IL-2 and recombinant IL-12 for the in vitro production of interferon gamma by canine peripheral blood mononuclear cells

BACKGROUND: Very few studies have been carried out so far aiming at modulating cellular immune responses in dogs. In this study, we evaluated the ability of recombinant canine IL-2 (rcaIL-2) and IL-12, in the form of a single-chain fusion protein (rsccaIL-12), to stimulate peripheral blood mononucle...

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Detalhes bibliográficos
Main Authors: Pereira, Andrea Mendes, de Pinheiro, Cristiane Garboggini Melo, dos Santos, Lenita Ramires, Teixeira, Naiara Carvalho, Chang, Yung-Fu, Pontes-de-Carvalho, Lain Carlos, de Sá Oliveira, Geraldo Gileno
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109786/
https://ncbi.nlm.nih.gov/pubmed/25037233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-460
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