HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms

Oxidized 1-palmitoyl-2-arachidonyl-sn-glycero-3-phospholcholine (OxPAPC) and its component phospholipids accumulate in atherosclerotic lesions and regulate the expression of >1,000 genes, many proatherogenic, in human aortic endothelial cells (HAECs). In contrast, there is evidence in the literat...

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Bibliographische Detailangaben
Hauptverfasser: Emert, Benjamin, Hasin-Brumshtein, Yehudit, Springstead, James R., Vakili, Ladan, Berliner, Judith A., Lusis, Aldons J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109762/
https://ncbi.nlm.nih.gov/pubmed/24859737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047738
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