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Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades

During the last 80 years there have been extraordinary advances in our knowledge of the chemistry and biology of bile acids. We present here a brief history of the major achievements as we perceive them. Bernal, a physicist, determined the X-ray structure of cholesterol crystals, and his data togeth...

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Autores principales: Hofmann, Alan F., Hagey, Lee R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109754/
https://ncbi.nlm.nih.gov/pubmed/24838141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R049437
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