Architecture of the Mediator Head module

Mediator is a key regulator of eukaryotic transcription(1), connecting activators and repressors bound to regulatory DNA elements with RNA polymerase II (Pol II) (1-4). In the yeast S. cerevisiae, Mediator comprises 25 subunits with a total mass over 1 MDa (5,6), and is organized into three modules,...

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Hauptverfasser: Imasaki, Tsuyoshi, Calero, Guillermo, Cai, Gang, Tsai, Kuang-Lei, Yamada, Kentaro, Cardelli, Francesco, Erdjument-Bromage, Hediye, Tempst, Paul, Berger, Imre, Kornberg, Guy Lorch, Asturias, Francisco J., Kornberg, Roger D., Takagi, Yuichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109712/
https://ncbi.nlm.nih.gov/pubmed/21725323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10162
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