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Architecture of the Mediator Head module
Mediator is a key regulator of eukaryotic transcription(1), connecting activators and repressors bound to regulatory DNA elements with RNA polymerase II (Pol II) (1-4). In the yeast S. cerevisiae, Mediator comprises 25 subunits with a total mass over 1 MDa (5,6), and is organized into three modules,...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109712/ https://ncbi.nlm.nih.gov/pubmed/21725323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10162 |
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