Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome

BACKGROUND. Hepatitis C virus (HCV) infects approximately 170 million people worldwide and may lead to cirrhosis and hepatocellular carcinoma in chronically infected individuals. Treatment is rapidly evolving from IFN-α–based therapies to IFN-α–free regimens that consist of directly acting antiviral...

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Detalhes bibliográficos
Main Authors: Meissner, Eric G., Wu, David, Osinusi, Anu, Bon, Dimitra, Virtaneva, Kimmo, Sturdevant, Dan, Porcella, Steve, Wang, Honghui, Herrmann, Eva, McHutchison, John, Suffredini, Anthony F., Polis, Michael, Hewitt, Stephen, Prokunina-Olsson, Ludmila, Masur, Henry, Fauci, Anthony S., Kottilil, Shyamasundaran
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109554/
https://ncbi.nlm.nih.gov/pubmed/24983321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75938
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