Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα

Hepatosteatosis is characterized by an aberrant accumulation of triglycerides in the liver; however, the factors that drive obesity-induced fatty liver remain largely unknown. Here, we demonstrated that the secreted cell adhesion protein periostin is markedly upregulated in livers of obese rodents a...

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Detaylı Bibliyografya
Asıl Yazarlar: Lu, Yan, Liu, Xing, Jiao, Yang, Xiong, Xuelian, Wang, E, Wang, Xiaolin, Zhang, Zhijian, Zhang, Huijie, Pan, Lingling, Guan, Youfei, Cai, Dongsheng, Ning, Guang, Li, Xiaoying
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109546/
https://ncbi.nlm.nih.gov/pubmed/25003192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74438
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