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Regulated proteolysis of the alternative sigma factor SigX in Streptococcus mutans: implication in the escape from competence

BACKGROUND: SigX (σ(X)), the alternative sigma factor of Streptococcus mutans, is the key regulator for transcriptional activation of late competence genes essential for taking up exogenous DNA. Recent studies reveal that adaptor protein MecA and the protease ClpC act as negative regulators of compe...

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Detalhes bibliográficos
Main Authors: Dong, Gaofeng, Tian, Xiao-Lin, Gomez, Zubelda A, Li, Yung-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109385/
https://ncbi.nlm.nih.gov/pubmed/25005884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-14-183
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