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Regulated proteolysis of the alternative sigma factor SigX in Streptococcus mutans: implication in the escape from competence

BACKGROUND: SigX (σ(X)), the alternative sigma factor of Streptococcus mutans, is the key regulator for transcriptional activation of late competence genes essential for taking up exogenous DNA. Recent studies reveal that adaptor protein MecA and the protease ClpC act as negative regulators of compe...

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Main Authors: Dong, Gaofeng, Tian, Xiao-Lin, Gomez, Zubelda A, Li, Yung-Hua
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109385/
https://ncbi.nlm.nih.gov/pubmed/25005884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-14-183
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