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Reduced hypothalamic-pituitary-adrenal axis activity in chronic multi-site musculoskeletal pain: partly masked by depressive and anxiety disorders

BACKGROUND: Studies on hypothalamic-pituitary-adrenal axis (HPA-axis) function amongst patients with chronic pain show equivocal results and well-controlled cohort studies are rare in this field. The goal of our study was to examine whether HPA-axis dysfunction is associated with the presence and th...

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Main Authors: Generaal, Ellen, Vogelzangs, Nicole, Macfarlane, Gary J, Geenen, Rinie, Smit, Johannes H, Penninx, Brenda WJH, Dekker, Joost
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109382/
https://ncbi.nlm.nih.gov/pubmed/25007969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-15-227
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