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Cell Types, Network Homeostasis, and Pathological Compensation from a Biologically Plausible Ion Channel Expression Model

How do neurons develop, control, and maintain their electrical signaling properties in spite of ongoing protein turnover and perturbations to activity? From generic assumptions about the molecular biology underlying channel expression, we derive a simple model and show how it encodes an “activity se...

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Autori principali: O’Leary, Timothy, Williams, Alex H., Franci, Alessio, Marder, Eve
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109293/
https://ncbi.nlm.nih.gov/pubmed/24853940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.04.002
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