DIURNAL RHYTHMICITY IN THE TRANSCRIPTION OF JEJUNAL DRUG TRANSPORTERS

Intestinal drug efflux proteins play a major role in the pharmacokinetics of many drugs. We assessed diurnal rhythmicity in the expression of ten major drug transporters. We acquired male Sprague-Dawley rats and harvested jejunal mucosa at 3-hourly intervals across a 24-hour period. qPCR was perform...

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Detaylı Bibliyografya
Asıl Yazarlar: Stearns, Adam T., Balakrishnan, Anita, Rhoads, David B., Ashley, Stanley W., Tavakkolizadeh, Ali
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109053/
https://ncbi.nlm.nih.gov/pubmed/18787306
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