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LRIG1 Enhances Chemosensitivity by Modulating BCL-2 Expression and Receptor Tyrosine Kinase Signaling in Glioma Cells

PURPOSE: Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) are an inhibitor of receptor tyrosine kinases (RTKs) that was discovered in recent years, and many studies showed that LRIG1 is a tumor suppressor gene and may be related to tumor drug resistance. In this study, we explored whet...

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Detalhes bibliográficos
Main Authors: Guo, Zhentao, Chen, Qianxue, Liu, Baohui, Tian, Daofeng, Zhang, Shenqi, Li, Mingchang
Formato: Artigo
Idioma:Inglês
Publicado em: Yonsei University College of Medicine 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108802/
https://ncbi.nlm.nih.gov/pubmed/25048475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2014.55.5.1196
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