Phase I Dose-Escalation Study of Nimustine in Tumor-Bearing Dogs

Nimustine (ACNU) is an alkylating agent of the nitrosourea and can be an antineoplastic agent in dogs. But, there has been no report on its dose-limiting toxicity (DLT) in dogs. This study was a phase I dose-escalation clinical trial to determine the maximum tolerated dose (MTD) and DLT of ACNU in t...

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Detalhes bibliográficos
Main Authors: TAKAHASHI, Masashi, GOTO-KOSHINO, Yuko, FUKUSHIMA, Kenjiro, KANEMOTO, Hideyuki, NAKASHIMA, Ko, FUJINO, Yasuhito, OHNO, Koichi, ENDO, Yasuyuki, TSUJIMOTO, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Veterinary Science 2014
Assuntos:
Internal Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108775/
https://ncbi.nlm.nih.gov/pubmed/24521794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.13-0345
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