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Proteasome-mediated processing of Nrf1 is essential for the coordinate induction of all proteasome subunits and p97
BACKGROUND: Proteasome inhibitors are widely used in treatment of multiple myeloma and as research tools. Diminished proteasome function also may contribute to neuronal dysfunction. In response to these inhibitors, cells enhance the expression of proteasome subunits by the transcription factor Nrf1....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108618/ https://ncbi.nlm.nih.gov/pubmed/24998528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.06.004 |
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