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Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naïve precursors()
A subset of human regulatory T cells (Tregs) secretes IL-17 and thus resembles Th17 effector cells. How IL-17+Treg cells differentiate from naïve precursors remains unclear. Here, we show that IL-17-producing T-cells can differentiate from CCR6+ naïve T cell precursors in the presence of IL-2, IL-1β...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108575/ https://ncbi.nlm.nih.gov/pubmed/24958901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302936 |
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