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Intestinal inflammation modulates expression of the iron regulating hormone hepcidin depending on erythropoietic activity and the commensal microbiota()

States of chronic inflammation such as inflammatory bowel disease are often associated with dysregulated iron metabolism and the consequent development of an anemia that is caused by maldistribution of iron. Abnormally elevated expression of the hormone hepcidin, the central regulator of systemic ir...

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Detalhes bibliográficos
Main Authors: Shanmugam, Nanda Kumar N., Trebicka, Estela, Fu, Ling-lin, Shi, Hai Ning, Cherayil, Bobby J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108560/
https://ncbi.nlm.nih.gov/pubmed/24973448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400278
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