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Nitric oxide regulates B cell activating factor (BAFF) expression and T-cell independent antibody responses()

While nitric oxide (NO) is known to regulate T cell responses, its role in regulating B cell responses remains unclear. Previous studies suggested that inducible NO synthase 2 (NOS2/iNOS) is required for normal IgA Ab responses but inhibits anti-viral IgG2a Ab responses. Here we used NOS2(−/−) mice...

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Detalhes bibliográficos
Main Authors: Giordano, Daniela, Draves, Kevin E., Li, Chang, Hohl, Tobias M., Clark, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108544/
https://ncbi.nlm.nih.gov/pubmed/24951820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303158
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