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Conformational Dynamics of Thermus aquaticus DNA Polymerase I during Catalysis

Despite the fact that DNA polymerases have been investigated for many years and are commonly used as tools in a number of molecular biology assays, many details of the kinetic mechanism they use to catalyze DNA synthesis remain unclear. Structural and kinetic studies have characterized a rapid, pre-...

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Detalhes bibliográficos
Main Authors: Xu, Cuiling, Maxwell, Brian A., Suo, Zucai
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108498/
https://ncbi.nlm.nih.gov/pubmed/24931550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.06.003
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