PIK3CA Gene Mutations and Overexpression: Implications for Prognostic Biomarker and Therapeutic Target in Chinese Esophageal Squamous Cell Carcinoma

AIMS: To evaluate PIK3CA gene mutations and PIK3CA expression status in Chinese esophageal squamous cell carcinoma (ESCC) patients, and their correlation with clinicopathological characteristics and clinical outcomes. METHODS: Direct sequencing was applied to investigate mutations in exons 9 and 20...

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Detalhes bibliográficos
Main Authors: Wang, Lin, Shan, Ling, Zhang, Shaokai, Ying, Jianming, Xue, Liyan, Yuan, Yanling, Xie, Yongqiang, Lu, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108430/
https://ncbi.nlm.nih.gov/pubmed/25054828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103021
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