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PIK3CA Gene Mutations and Overexpression: Implications for Prognostic Biomarker and Therapeutic Target in Chinese Esophageal Squamous Cell Carcinoma
AIMS: To evaluate PIK3CA gene mutations and PIK3CA expression status in Chinese esophageal squamous cell carcinoma (ESCC) patients, and their correlation with clinicopathological characteristics and clinical outcomes. METHODS: Direct sequencing was applied to investigate mutations in exons 9 and 20...
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Hauptverfasser: | , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108430/ https://ncbi.nlm.nih.gov/pubmed/25054828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103021 |
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