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Huntingtin Is Critical Both Pre- and Postsynaptically for Long-Term Learning-Related Synaptic Plasticity in Aplysia

Patients with Huntington’s disease exhibit memory and cognitive deficits many years before manifesting motor disturbances. Similarly, several studies have shown that deficits in long-term synaptic plasticity, a cellular basis of memory formation and storage, occur well before motor disturbances in t...

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Autors principals: Choi, Yun-Beom, Kadakkuzha, Beena M., Liu, Xin-An, Akhmedov, Komolitdin, Kandel, Eric R., Puthanveettil, Sathyanarayanan V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108396/
https://ncbi.nlm.nih.gov/pubmed/25054562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103004
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