The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation

Organisms have evolved elaborate mechanisms to adjust intracellular nutrient levels in response to fluctuating availability of exogenous nutrients. During starvation, cells can enhance amino acid uptake and synthesis through the general amino acid control (GAAC) pathway, whereas nonessential cellula...

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Detalhes bibliográficos
Main Authors: Chen, Rui, Zou, Yilong, Mao, Dongxue, Sun, Daxiao, Gao, Guanguang, Shi, Jingwen, Liu, Xiaoqing, Zhu, Chen, Yang, Mingyu, Ye, Wanlu, Hao, Qianqian, Li, Ruiqiang, Yu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107793/
https://ncbi.nlm.nih.gov/pubmed/25049270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403009
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