Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity

Adenosine triphosphate (ATP) synthase β, the catalytic subunit of mitochondrial complex V, synthesizes ATP. We show that ATP synthase β is deacetylated by a human nicotinamide adenine dinucleotide (NAD(+))–dependent protein deacetylase, sirtuin 3, and its Drosophila melanogaster homologue, dSirt2. d...

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Detalhes bibliográficos
Main Authors: Rahman, Motiur, Nirala, Niraj K., Singh, Alka, Zhu, Lihua Julie, Taguchi, Kaori, Bamba, Takeshi, Fukusaki, Eiichiro, Shaw, Leslie M., Lambright, David G., Acharya, Jairaj K., Acharya, Usha R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107778/
https://ncbi.nlm.nih.gov/pubmed/25023514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404118
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