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Elobixibat and its potential role in chronic idiopathic constipation
Chronic idiopathic constipation is highly prevalent among adults. Bile acids (BAs) and the enterohepatic BA circulation modulate colonic secretion and motility that affect transit. BAs in the colon have a dual action as osmotic and stimulant agents. Newer agents, such as elobixibat (A3309), an inhib...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107709/ https://ncbi.nlm.nih.gov/pubmed/25057297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X14528269 |
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